It was first described by schultz in 1927 as an orthokeratinized variant of the formerly called odontogenic keratocyst, today known as the keratocystic odontogenic tumour. The glandular odontogenic cyst is a rare odontogenic cyst. We present a case of aot in a 14yearold male who was misdiagnosed as dentigerous cyst. Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by. Jul 31, 2017 image result for calcifying odontogenic cyst. Clinically, it presents no tendency to relapse due to low local aggressiveness, and. Abstractdentigerous cyst dc is one of the most common odontogenic cysts of the jaws and. Orthokeratinized odontogenic cyst ooc is a developmental cyst that occurs in the maxilla and the mandible and is defined by the world health organization as the uncommon orthokeratinized type of odontogenic keratocyst okc. They are benign odontogenic cysts that are associated with the crowns of permanent unerrupted teeth. On imaging, they usually present as a welldefined and unilocular radiolucency surrounding the crown of an unerupted or impacted tooth within the mandible. The orthokeratinized odontogenic cyst ooc was first described by schultz 1 in 1927 as a dermoid cyst, and in 1945, it was considered by philipsen 2 as an eventual type of odontogenic keratocyst okc. Non odontogenic jaw cysts are cysts arising from epithelial remnants of embryonic ducts left behind after embryonal facial and jaw development. Since the glandular odontogenic cyst can range in size, treatment can be as simple as enucleation and curettage to.
It has been reported predominantly as an incidental. Adenomatoid odontogenic tumor aot is a wellrecognised slow growing benign tumor derived from complex system of dental lamina or its remnants. Odontogenic cysts and tumors are growths that are usually involved in the process of tooth development or odontogenesis. After excluding cysts occurring along the lateral buccal surface of a partially impacted mandibular molar of a young individual, the term paradental cyst also refers to a variant of the dentigerous cyst with an inflammatory, rather than developmental pathogenesis the two most common scenarios include vital nonnecrotic teeth. In 85% of cases, it is found in the mandible, especially in anterior areas. It is most common in people in their second to third decades but can be seen at almost any age.
Diagnostic factors of odontogenic cysts in iranian population. Orthokeratinized odontogenic cyst ooc is a relatively rare lesion of the jaws, mainly located in the posterior segment of the mandible 1,3. Since radical procedures are suggested for kcot in contrast to dentigerous cyst, the histological investigation of this entity has been the focus of many studies 17. The orthokeratinized odontogenic cyst ooc is a developmental odontogenic cyst relatively rare, arising from the cell rests of the dental lamina 1, 2. Radicular cyst, dentigerous cyst, surgical cyst management, cyst pathology. The new classification of head and neck tumours was published by the world health organisation in july 2005 barnes et al. Introduction odontogenic cysts are probably the most common tissue degrading lesions of the maxillofacial skeleton. Left maxillary cystic lesion associated with the crown of the unerupted molar tooth 28 in keeping with an odontogenic keratocyst given the bony expansion.
The following classification system is a modification of the world health organization. Odontogenic cyst are a group of jaw cysts that are formed from tissues involved in odontogenesis tooth development. Identical to structures present in lateral periodontal cysts or botryoid odontogenic cysts or soft tissue odontogenic cyst, gingival cyst of adult. Article information, pdf download for glandular odontogenic cyst. Introduction the frequency of odontogenic cysts in children is relatively low. The free text terms used were orthokeratinised odontogenic cyst or orthokeratinized odontogenic cyst. Odontogenic cysts, tumors, and related jaw lesions ento key. Glandular odontogenic cyst goc, accepted by who 1992 sialoodontogenic cyst polymorphous odontogenic cyst mucoepidermoid odontogenic cyst epidemiology.
In the 4th edition of who classification of head and neck tumors 2017. Recognition of ooc as a unique entity is of utmost importance as it bears. Orthokeratinized odontogenic cyst ooc is a relatively uncommon developmental cyst of the jaw constituting about 10%. Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by expansion, causing displacement of adjacent teeth 3. A dentigerous cyst results because of the enlargement of the follicular space of the whole or part of the crown of an impacted or. It is more common in adults in their fifth and sixth decades.
The orthokeratinized odontogenic cyst ooc 1 was first clearly identified as an orthokeratinzed variant of the odontogenic keratocyst by wright in 1981 2 owing to its different histopathology and reduced likelihood to recur. Article information, pdf download for calcifying odontogenic cyst. The recently published new who classification of head and neck tumours does not include the entity globulomaxillary cyst, and no mention of these cysts is made in the section on odontogenic cysts barnes et al. Odontogenic and nonodontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. Immunohistochemical study of the orthokeratinized odontogenic.
The cyst lining forms as the epithelial elements proliferate. The ooc is a developmental odontogenic cyst relatively rare. Calcifying odotogenic cyst is a benign odontogenic tumor of cystic type most likely to affect the anterior areas of the jaws. Synonyms for calcifying odontogenic cyst in free thesaurus. Keratocystic odontogenic tumor kcot presents most frequently in the second, third and fourth decades of life 54. The histopathological examination showed bilateral orthokeratinized odontogenic cyst. Botryoid odontogenic cyst it is a variant of lateral odontogenic cyst, but that the term botryoid odontogenic cyst should be retained because of the tendency of this variant to recur if inadequately removed. Calcifying odontogenic cyst coc is a rare odontogenic cyst with.
Has many features of odontogenic tumor, therefore it is placed in the category of tumors in the latest who classification of odontogenic cysts and tumors. Hyperchromatic, cuboidal or columnar basal cell layer 3. Kcot can be associated with the naevoid basal cell carcinoma syndrome nbccs. This lesion is categorised into three variants of which the more common variant is follicular type which is often mistaken for dentigerous cyst.
May 10, 2020 when a cyst forms near the base of a molar that has only partially erupted from the gum, it is called a paradental cyst. Calcifying odontogenic cyst synonyms, calcifying odontogenic. Treatment approaches for odontogenic cysts of the maxillary sinus. Also called as odontogenic ghost cell cyst or gorlin cyst. Who defined it as a cystic lesion in which the epithelial lining shows a welldefined basal layer of columnar cells, an overlying layer that is often many cells thick and that may resemble stellate reticulum, and masses of ghost epithelial cells that may be in the epithelial cyst lining or in the fibrous. Chapter 21 odontogenic and non odontogenic tumors of the jaws introduction. By definition, most kcots develop instead of a tooth, arising from the dental lamina. Image result for calcifying odontogenic cyst cysts.
Multiple cystic spaces similar to those seen in botryoid odontogenic cysts. If this mitotic activity is the major component of the cyst expansion, it may be better to consider the lesion a cystic neoplasm rather than a simple cyst. The orthokeratinized odontogenic cyst ooc is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumour kcot until wright 1981 defined it as a different entity. Calcifying odontogenic cyst was first described by gorlin et al. Although both the first two editions of the world health organizations who histological classification of odontogenic tumours recognized that cases. Odontogenic cysts a clinicopathological study manal a. However, a number of odontogenic cysts can be radiologically classified as globulomaxillary radiolucencies. Glandular odontogenic cyst 0 0 0 3 0 0 2 5 residual cyst 0 1 7 6 6 6 2 28. Odontogenic keratocyst okc is an aggressive cyst and its recurrence is higher than other odontogenic cysts, orthokeratinized odontogenic cyst ooc is a cyst with moderate biological behavior in. Sep 30, 2012 lateral periodontal cyst glandular odontogenic cyst unclassified paradental cyst calcifying odontogenic cyst 9. Dentigerous cysts, also called follicular cysts, are slow growing benign and noninflammatory odontogenic cysts that are thought to be developmental in origin.
In 1981, wright 3 specified its clinicopathologic aspects, assuring that ooc was an individual entity, distinct from other odontogenic cysts, including the okc. Glandular odontogenic cyst 0 0 0 3 0 0 2 5 residual cyst 0 1 7 6 6 6 2 28 orthokeratinized cyst 0 0 2 1 1 1 2 7 gingival cyst 0 0 1 0 0 0 0 1 eruption cyst 0 1 0 0 0 0 0 1 paradental cyst 0 0 5 0 0 0 0 5 total 29 89 6 85 49 30 16 434. These cysts surround the crown of a tooth that has not migrated into the. Cd166 expression in dentigerous cyst, keratocystic. Orthokeratinized odontogenic cyst ooc is a relatively rare odontogenic cyst, distinct from odontogenic keratocyst okc. Jul 31, 2017 jul 31, 2017 image result for calcifying odontogenic cyst stay safe and healthy. Okc, orthokeratinized odontogenic cysts ooc, dentigerous cysts dc, and ameloblastomas. Calcifying odontogenic cyst associated with dentigerous cyst in a. In onethird of cases, an impacted tooth is involved. Glandular odontogenic cyst goc is a relatively new entity and is defined as a cyst arising in the toothbearing areas of the jaws and characterized by an epithelial lining with cuboidal or columnar cells, both at the surface and lining, with crypts or cystlike spaces within the thickness of the epithelium. Surgical management of dentigerous cyst and keratocystic. It develops at the apex of an erupted tooth in response to pulpal necrosis secondary to dental caries or trauma.
This article is from journal of applied oral science, volume 20. Odontogenic cysts are closed sacs, and have a distinct membrane derived from rests of odontogenic epithelium. In contrast to other studies, the lesion was located in the body of mandible, starting from lower left canine region involving lower left premolars. Papillary projections or tufting of epithelium into. Case report keratocystic odontogenic tumor simulating lateral. Orthokeratinized odontogenic cyst usually occurs most often between third and fourth and decades and with a male gender predilection. A dentigerous cyst results because of the enlargement of the follicular space of the whole or part of the crown of an impacted or unerupted tooth and is attached to the neck of the tooth. Glandular odontogenic cyst goc is a relatively rare but. On radiographs, the calcifying odontogenic cyst appears as a unilocular radiolucency dark area. Gorlin cysts, also called calcifying odontogenic cysts, typically form in the front part of the jaw and are often associated with an impacted tooth.
The cyst arises from inflammatory stimulation and proliferation of the rests of malassez. Odontogenic and non odontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. Microscopically, the lesion is similar to the lateral periodontal cyst but exhibits some differences. A glandular odontogenic cyst is an extremely isolated cyst found in the. Glandular odontogenic cyst wikizero free encyclopedia. Odontogenic cysts, tumors, and related jaw lesions preceptor. It is not until 1981 that wright defines this as an.
On radiographs, it can appear as a unilocular or multilocular radiolucency dark area. Glandular odontogenic cyst sialo odontogenic cyst very rare odontogenic cyst a benign cystic neoplasm of odontogenic origin. Please practice handwashing and social distancing, and check out our resources for adapting to these times. Lateral periodontal cyst glandular odontogenic cyst unclassified paradental cyst calcifying odontogenic cyst 9. These cysts are closed sacs that may contain air, fluids, or semisolid materials enclosed in a distinct membrane that is usually a biproduct of odontogenic epithelium. Chapter 21 odontogenic and nonodontogenic tumors of the jaws introduction. Odontogenesis, odontogenic cysts, and odontogenic tumors. Lateral periodontal cyst lpc is a relatively rare odontogenic pathology, representing about 0. Image result for calcifying odontogenic cyst cysts, pathology. Primordial cyst the kcot is the least common, but most dangerous odontogenic cyst. Although most common discovered in the second and third decades, they may be found at any age 1, 6.
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